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Thalidomide 4-fluoride
CAS No. 835616-60-9
Thalidomide 4-fluoride( E3 ligase Ligand 4 )
Catalog No. M28566 CAS No. 835616-60-9
Thalidomide 4-fluoride (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 26 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameThalidomide 4-fluoride
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NoteResearch use only, not for human use.
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Brief DescriptionThalidomide 4-fluoride (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein.
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DescriptionThalidomide 4-fluoride (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.
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In Vitro——
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In Vivo——
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SynonymsE3 ligase Ligand 4
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PathwayImmunology/Inflammation
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TargetIRAK
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RecptorPotassium Channel
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Research Area——
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Indication——
Chemical Information
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CAS Number835616-60-9
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Formula Weight276.223
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Molecular FormulaC13H9FN2O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 300 mg/mL (1086.09 mM)
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SMILESFc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Davies PJ, Thomas EA, Bornstein JC. Different types of potassium channels underlie the long afterhyperpolarization in guinea-pig sympathetic and enteric neurons. Auton Neurosci. 2006 Jan 30;124(1-2):26-30.
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